Frotoconservational (or cold mist) has made a revolution in health care. Millions of people have created families with frozen sperm, eggs and embryos, and frozen ovarian tissue to help restore the fertility of women who have lost their ability to give birth due to chemotherapy. Bigthink.com information portal speak About the source of coldness and what is waiting for technology in the future.
In the 1930s, farmers in the United States, the Russian Federation and other parts of the world used artificial insemination to raise livestock. This process not only provides the best fertilizer ratio compared to natural reproduction, but also reduces the amount of sperm necessary for pregnancy. And this means a high -quality man who can fertilize more women.
One of the biggest issues in this matter is the effectiveness of the procedure. Although sperm mixture has a special environment based on egg yolks and the cooling of this mixture lasts expired, farmers only have a few days between sperm fence and fertilization. The effort to freeze it to use the next leads to the appearance of ice crystals on sperm cells, resulting in an irreversible cell damage.
But in 1949, a breakthrough occurred. British biologist Christopher Polzh discovered that he removed healthy chickens from frozen sperm and melting the rooster due to glycerin addition. He plays the role of the cold, protecting sperm from damage in frost. After that, he did this technique for sperm.
After opening the Polzh group, similar experiments started American biologist Jerome Sherman, but he decided to conduct experiments on human cells. Sherman discovered that sperm is easily frozen easily if you first focus them with centrifuges. After mixing the cells with the glycerin and medium mixture, he slowly froze the material, and then hold it on the dry ice.
In 1953, the first three children were conceived with the help of cold sperm. Before the end of the 20th century, scientists discovered the accurate combination of techniques, chemicals and cooling methods to successfully preserve eggs, embryos, blood cells, allranplands da and more.
After that, scientists (and fantasy writers) had a thorough use of technology: freezing and storing everyone.
People hope that the conservation of the human body after death will help preserve and revive the deceased in the future, when science will open a treatment for its disease. And it doesn't matter how much time between death and miraculous healing – many years, decades or even centuries may have passed in theory. Therefore, in 1967, psychology professor James Bedford became the first person with a cold -frosting corpse. And about 500 follow him.
So far, the conservation of Cryoponation of cells and tissue has become a frequent part of medicine, however, the scope of Cryonics, is involved in the freezing of a person after death, retaining the conflict. Some scientists are doubting the morality of the efforts to deceive Muslim death with the help of frozen technologies. Others say that companies that sell such services are profitable for patients and those who are afraid of death. For reference, some companies take from $ 200,000 each body.
Even if the doctors of the future can cure the causes of the death of freezing, their body is likely to be damaged by revival. The nightmare of those who have defrosted and checked without inspiration for confidence.
But this does not mean that we will never find people's freezing ways. In addition, scientists can perform equally important discoveries in parallel will positively affect the field of health care. Cryobiology is nothing more than a technical issue. Having biological knowledge, you just need to find solutions for certain limitations.
One of these limitations lies in a simple fact: freezing and defrosting something small, such as 100 cell embryos, much easier than the whole body. The center of the object is thawed slower than the outer layers and the temperature difference contributes to the formation of ice crystals that damage the tissue.
In July 2023, the staff of the University of Minnesota said they were opened in this regard. For scientific works published in the Nature Communications magazine, they added to the prophets of iron nanoparticles, then they pumped it through the kidneys in the lab. But instead of cooling them slowly, scientists quickly freeze them with liquid nitrogen. This method is called pureization; It causes cells to go into a state of glass. It is widely used in embryo conservation, because it leads to much smaller cell damage.
The kidneys were left in the warehouse for up to 100 days, after which the group of scientists placed frozen organs inside the copper roll and missed the current through it. The magnetic field from iron microscopes in the kidneys, so that it can defrost the organs smoothly for about a minute and a half. Later, scientists washed the kidneys from grooves and moved them to five mice. The first two or three weeks they did not fully work, but then they normalized. A month later, the buds were not different from fresh implants.
Of course, mouse buds cannot be called big – usually weighing more than one gram. But at the same time, they contain tens of millions of cells at least 20 different types, making them larger and more complicated than embryos. It does not mention the fact that the fact of successfully freezing, defrosting and transplanting any mammal is an important milestone for science. It is likely that it will pave the way that many people consider to be the following important stage of the refrigerant – creating a bank of human organs.